
Polynucleotide Treatment in Colchester
Doctor-led Plinest Polynucleotide treatments designed to rejuvenate and restore your skin’s natural radiance.

Polynucleotide Treatment in Colchester
Doctor-led Plinest Polynucleotide treatments designed to rejuvenate and restore your skin’s natural radiance.

Polynucleotide Treatment in Colchester
Doctor-led Plinest Polynucleotide treatments designed to rejuvenate and restore your skin’s natural radiance.
Introducing Polynucleotides in Colchester
At Bespoke Medical Aesthetics in Stanway, Colchester, we are proud to offer Plinest Polynucleotide treatments — a new generation of injectable biostimulators that support your skin’s natural ability to renew itself.
Polynucleotides are designed to improve skin texture, firmness and hydration through gentle regeneration at a cellular level. Ideal for those seeking a natural, refreshed appearance, this treatment is performed exclusively by a qualified medical doctor using advanced, evidence-based techniques.
How Polynucleotides Work
Skin Repair and Hydration
Polynucleotides are biostimulating molecules made up of highly purified DNA fragments. The Plinest range used at Bespoke Medical Aesthetics is derived from salmon and trout DNA, processed under the highest pharmaceutical standards to ensure safety, purity and efficacy.
These DNA molecules act like a nutrient source or “food” for the skin’s cells — encouraging them to repair, regenerate and function more efficiently. By supporting the skin’s natural renewal processes, Polynucleotides help to stimulate collagen and elastin, improve hydration, and restore a healthy, radiant appearance.
This approach sits within the emerging field of regenerative aesthetics, focusing on improving skin quality from within rather than simply masking signs of ageing.
Key benefits:
Improves overall skin quality and elasticity
Enhances hydration and radiance
Supports collagen and elastin stimulation
Helps smooth fine lines and crepey texture
- Suitable for delicate areas such as the under-eyes and neck
- Promotes a natural, gradual rejuvenation rather than an artificial change

Treatment Areas & Process
Polynucleotides are suitable for multiple areas, especially where the skin feels dull, crepey or tired.
Polynucleotides can be used on the following areas:
Face
Neck and décolletage
Under-eye area (tear trough rejuvenation)
Hands
- ‘Smokers lines’ (peri-oral)
Treatment Process:
Comprehensive consultation with your doctor to assess your skin goals
A series of microinjections using Plinest polynucleotides
Mild redness or swelling may occur for 24–48 hours
Recommended course: 3 sessions, spaced 3–4 weeks apart, with maintenance every few months
Results develop gradually, leaving your skin renewed, hydrated and refreshed.*
*Results vary individually.

Polynucleotides vs Profhilo
Both Polynucleotides and Profhilo are injectable bio-stimulating treatments, but they work in different ways.
Profhilo contains pure hyaluronic acid to deeply hydrate and improve firmness.
Polynucleotides use DNA-based molecules to stimulate regeneration and strengthen the skin’s underlying structure.
Clients often choose Polynucleotides for long-term structural improvement or to treat delicate areas such as under the eyes, while Profhilo is excellent for overall hydration and glow. Polynucleotides can also be combined with other treatments such as Skinvive, HarmonyCA, and medical-grade skincare giving synergistic results overall by regenerating the skin and enhancing hydration on different skin layers.
Your doctor will help you decide which treatment — or combination — best suits your goals.

Introductory Offer – Limited Time Only
To celebrate the introduction of Plinest Polynucleotide treatments, Bespoke Medical Aesthetics is offering an introductory consultation offer for new clients until November 30th, 2025.
Book your one-to-one consultation to discover how Polynucleotides can naturally enhance your skin’s health and radiance.
*Disclaimer: Results and treatment longevity vary between individuals and depend on several factors including skin quality, lifestyle, and age. All treatments are subject to a full medical consultation to ensure suitability. Polynucleotides are classed as injectable biostimulators designed to support skin regeneration and hydration; they are not a replacement for prescription-only treatments. Read more on clinical reviews on Polynucleotides.
FAQs About Polynucleotides
Q1: When will I see results from my polynucleotides treatment?
Results develop gradually over several weeks as your skin regenerates and collagen production increases.
Q2: How long do results from polynucleotides last?
Typically around 6–9 months, with maintenance recommended 2–3 times per year.
Q3: Which areas can be treated with polynucleotides?
Polynucleotides can be used to treat many areas of the body where skin is crepy, tired or dull. The most common areas treated include:
- Face
- Under eye area (tear trough)
- Around the mouth (often to address vertical lip lines ‘smokers lines)
- Neck
- Décolletage
- Back of hands
Q4: Is there any downtime after polynucleotide treatment?
Downtime in most cases is minimal — mild redness or swelling may appear and usually resolves within 24–48 hours.
Q5: Can Polynucleotides be combined with other treatments?
Yes. Polynucleotides complement other skin rejuvenation options such as Profhilo, SkinVive, or medical-grade skincare.
Q6: Who performs the treatment?
All treatments are performed by Dr Elaine O’Connor-Haq, an advanced aesthetic doctor with a background in medicine, pharmacy, and holistic skin health.